This government-backed startup is growing blood to help fight shortages

Last month, the American Red Cross declared an emergency blood shortage after its national supply fell by more than 25% in July. One startup's solution: Lab-grown blood.

Shortages can be dire for patients since doctors have to make tough decisions about who needs blood transfusions the most. The American Red Cross collects and distributes about 40% of the U.S.' blood supply, per its website, and the organization is imploring more people to donate. 

But if Doug McConnell has his way, hospitals and clinics won't have to rely on donations forever. McConnell is CEO of a four-year-old startup called Safi Biotherapeutics, which is working to manufacture inexpensive red blood cells at scale. 

Scientists have already discovered how to grow red blood cells from stem cells, but it's a costly and complex process that typically yields small amounts at a time. In November 2022, for instance, researchers in the U.K. successfully transfused about one or two teaspoons of manufactured blood into people as part of a clinical trial. 

Safi's goal is to build on these advancements and produce large quantities of blood that could eventually be used commercially to help care for patients and avoid blood shortages. 

"People have tried, but the technology has evolved and we see this path now," McConnell told CNBC in an interview. "I do think it goes from science fiction to science, but still a lot of work ahead. No question about that." 

Safi has received more than $16 million to date from the U.S. Department of Defense, and that total could exceed $20 million by the end of the year thanks to an additional in-process grant. The company also recently announced an additional $5 million in seed funding led by J2 Ventures. McConnell said this combined