The most expensive home for sale in the U.S. goes up for $295 million in Naples, Florida

The most expensive home for sale in the U.S. hit the market this week for $295 million.

Gordon Pointe, as it's called, is a roughly 9-acre compound in Naples, Florida, on the Gulf Coast, in an affluent enclave called Port Royal.

The mega-listing includes a main house that spans about 11,500 square feet, with six bedrooms. Two guest houses, each over 5,000 square feet, bring the estate's total interior living space to 22,800 square feet. All three homes are on a peninsula that delivers 1,650 feet of waterfront, a private yacht basin and T-shaped dock.

Before you start counting up bedrooms and calculating the price per square foot (which is about $12,900), co-listing agent Leighton Candler of Corcoran told CNBC the value here isn't so much about the size of the three grand homes on the property, it's about privacy, beach frontage and a rare opportunity for significant development.

According to a press release that launched the listing, "The property can accommodate more than 200,000 square feet of residential development," meaning the land has a ton of untapped potential.

"There can be eight waterfront homes on this property," Candler told CNBC. While the property could be broken apart after purchase, the New York-based broker speculates a potential buyer will more likely maintain it as a private family compound.

The nine acres are made up of contiguous lots, the first of them purchased in 1985 by John and Rhodora Donahue. John Donahue co-founded a Pittsburgh-based investment management firm, now known as Federated Hermes, with over $758 billion in assets under management, according to the firm's website.

After that first purchase in 1985, the Donahues continued to buy up more of the peninsula and didn't stop until they owned it